Zydena 100 mg an oral prescription medication for treatment of men erectile dysfunction.
Zydena 100 mg
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Zydena 100 mg
Zydena 100 mg is originaly developed by the Korean firm Dong-A PharmTech Co. Ltd.Zydena 100 mg is a phosphodiesterase type5 (PDE5) inhibitor.Zydena 100 mg produced highly significant improvement in erectile function after 12 weeks of drug therapy with up to a 92% vaginal penetration success rate compared to 53% for the placebo group and up to 76% intercourse completion rate compared to 15% for the placebo group, in various Phase 2 and 3 clinical studies.The overall patient satisfaction as measured by the standard global assessment question was up to 89% in the high dose Zydena 100 mg treatment group compared to 26% in the placebo group.
Zydena 100 mgalso has a unique pharmacokinetic profile (Tmax of 1.0-1.5 hours and a half-life of 11-13 hours) suggesting that the drug could have a relatively rapid onset and sufficiently long duration to make it effective for up to 24 hours.Sexual activity is a potential risk for patients with cardiovascular disease, hypertension, so treatment of sexual dysfunctions, including use of Zydena, should not hold for men with heart disease, in which sexual activity is not recommended. Zydena is a drug for treatment of erectile dysfunction. Is a reversible selective inhibitor of cGMP-specificphosphodiesterasetype5. Zydena no direct relaxing effect on isolated corpus cavernosum, but enhances sexual stimulation relaxing effect of nitric oxide by inhibiting PDE-5, responsible for the breakdown of cGMP in the cavernous body. The result is relaxation of smooth muscles of arteries and blood flow to the tissues of the penis that causes erections. The drug has no effect in the absence of sexual stimulation.
Zydena 100 mg improves erection and the possibility of successful sexual intercourse. The action of the drug has an optimal duration - up to 24 h. The effect is manifested as early as 30 minutes after taking the drug in the presence of sexual arousal.Patients with a barrier of outflow of blood from the left ventricle (an aortal stenosis) can be more sensitive to action of vazodilatator, including PDE inhibitors. Despite shortage of clinical tests of cases of long installation (more long, than 4 hours) and priapism (the painful installation lasting more than 6 h), such phenomena specific to this class of drugs. In case of the installation lasting more than 4 hours (irrespective of pain), patients should look for medical care immediately. For lack of timely processing of priapism can lead to irreversible damage capable to become straight fabrics and capable to become straight functions. For lack of clinical data on udenafil use in patients, is more senior, than 71 years this category which is not recommended for patients, taking drug. Zydena not recommended for use in a combination to other treatments capable to become straight dysfunctions.
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